Natural Factors MSM 1,000mg CapsulesTake 1 capsule, 2 3 times daily with meals for a minimum of 4 weeks to see results, avoid taking at bedtime, relieves joint pain due to osteoarthritis. FORMULATED AND PACKAGED IN CANADA, NON GMO AND ISURA TESTED Natural Factors MSM contains the naturally occurring sulfur compound methyl sulfonyl methane (MSM) to help relieve joint pain from osteoarthritis. Healthy connective tissue relies on a good supply of sulfur. MSM plays an important role in the